Drug safety evaluation

Medientyp: Buch

Titel: Drug safety evaluation

Beteiligte: Gautier, Jean-Charles [HerausgeberIn]

Erschienen: New York, NJ: Humana Press, [2017]

Enthält: Nonclinical development of combination drugs / Alberto Lodola
Nonclinical development of combination drugs / Alberto Lodola
Juvenile nonclinical safety studies in support of pediatric drug development / Paul C. Barrow and Georg Schmitt
Procedures of necropsy and tissue sampling / Laurence Fiette, Mohamed Slaoui, and Anne-Laure Bauchet
Tissue sampling and processing for histopathology evaluation / Mohamed Slaoui, Anne-Laure Bauchet, and Laurence Fiette
Principles and methods of immunohistochemistry / José A. Ramos-Vara
Applications of mass spectrometry imaging for safety evaluation / David Bonnel and Jonathan Stauber Part III Genetic Toxicology
In vivo rat T-lymphocyte Pig-a assay : detection and expansion of cells deficient in the GPI-anchored CD48 surface marker for analysis of mutation in the endogenous Pig-a gene / Vasily N. Dobrovolsky, Javier Revollo, Dayton M. Petibone, and Robert H. Heflich
Detection of in vivo mutation in the Pig-a gene of mouse bone marrow erythroids / Takafumi Kimoto and Daishiro Miura
Use of bacterial repair endonucleases in the comet assay / Andrew R. Collins
Automated patch-clamp methods for the hERG cardiac potassium channel / Sylvie Houtmann, Brigitte Schombert, Camille Sanson, Michel Partiseti, and G. Andrees Bohme
Impedance measurement in induced pluripotent stem cell-derived cardiomyocytes / Emma-Jane Poulton
Target safety assessment : strategies and resources / Richard J. Brennan
NMR and MS methods for metabolomics / Alexander Amberg, Björn Riefke, Götz Schlotterbeck, Alfred Ross, Hans Senn, Frank Dieterle, and Matthias Keck
Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR / Gabriel Baverel, Maha El Hage, and Guy Martin
Statistical analysis of auantitative RT-PCR results / Richard Khan-Malek and Ying Wang
Evaluation of mitochondrial respiration in cultured rat hepatocytes / Jean-Pierre Marchandeau and Gilles Labbe
FETAX assay for evaluation of developmental toxicity / Isabelle Mouche, Laure Malésic, and Olivier Gillardeaux
Evaluation of embryotoxicity using the Zebrafish model / Lisa Truong and Robert L. Tanguay
Absolute quantification of toxicological biomarkers via mass spectrometry / Thomas Y. K. Lau, Ben C. Collins, Peter Stone, Ning Tang, William M. Gallagher, and Stephen R. Pennington
Next-generation sequencing to investigate urinary microRNAs from Macaca fascicularis (cynomolgus monkey) / Yaligara Veeranagouda, Jean-François Léonard, Jean-Charles Gautier, and Eric Boitier
Quantitative RT-PCR for microRNAs in biofluids / Michael Thorsen, Thorarinn Blondal, and Peter Mouritzen
Chromogenic in situ hybridization methods for microRNA biomarker monitoring of drug safety and efficacy / Barbara R. Gould, Tina Damgaard, and Boye Schnack Nielsen
Urine exosome isolation and characterization / Jonathan M. Street, Erik H. Koritzinsky, Deonna M. Glispie, and Peter S.T. Yuen.
Juvenile nonclinical safety studies in support of pediatric drug development / Paul C. Barrow and Georg Schmitt
Procedures of necropsy and tissue sampling / Laurence Fiette, Mohamed Slaoui, and Anne-Laure Bauchet
Tissue sampling and processing for histopathology evaluation / Mohamed Slaoui, Anne-Laure Bauchet, and Laurence Fiette
Principles and methods of immunohistochemistry / José A. Ramos-Vara
Applications of mass spectrometry imaging for safety evaluation / David Bonnel and Jonathan Stauber Part III Genetic Toxicology
In vivo rat T-lymphocyte Pig-a assay : detection and expansion of cells deficient in the GPI-anchored CD48 surface marker for analysis of mutation in the endogenous Pig-a gene / Vasily N. Dobrovolsky, Javier Revollo, Dayton M. Petibone, and Robert H. Heflich
Detection of in vivo mutation in the Pig-a gene of mouse bone marrow erythroids / Takafumi Kimoto and Daishiro Miura
Use of bacterial repair endonucleases in the comet assay / Andrew R. Collins
Automated patch-clamp methods for the hERG cardiac potassium channel / Sylvie Houtmann, Brigitte Schombert, Camille Sanson, Michel Partiseti, and G. Andrees Bohme
Impedance measurement in induced pluripotent stem cell-derived cardiomyocytes / Emma-Jane Poulton
Target safety assessment : strategies and resources / Richard J. Brennan
NMR and MS methods for metabolomics / Alexander Amberg, Björn Riefke, Götz Schlotterbeck, Alfred Ross, Hans Senn, Frank Dieterle, and Matthias Keck
Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR / Gabriel Baverel, Maha El Hage, and Guy Martin
Statistical analysis of auantitative RT-PCR results / Richard Khan-Malek and Ying Wang
Evaluation of mitochondrial respiration in cultured rat hepatocytes / Jean-Pierre Marchandeau and Gilles Labbe
FETAX assay for evaluation of developmental toxicity / Isabelle Mouche, Laure Malésic, and Olivier Gillardeaux
Evaluation of embryotoxicity using the Zebrafish model / Lisa Truong and Robert L. Tanguay
Absolute quantification of toxicological biomarkers via mass spectrometry / Thomas Y. K. Lau, Ben C. Collins, Peter Stone, Ning Tang, William M. Gallagher, and Stephen R. Pennington
Next-generation sequencing to investigate urinary microRNAs from Macaca fascicularis (cynomolgus monkey) / Yaligara Veeranagouda, Jean-François Léonard, Jean-Charles Gautier, and Eric Boitier
Quantitative RT-PCR for microRNAs in biofluids / Michael Thorsen, Thorarinn Blondal, and Peter Mouritzen
Chromogenic in situ hybridization methods for microRNA biomarker monitoring of drug safety and efficacy / Barbara R. Gould, Tina Damgaard, and Boye Schnack Nielsen
Urine exosome isolation and characterization / Jonathan M. Street, Erik H. Koritzinsky, Deonna M. Glispie, and Peter S.T. Yuen.

Ausgabe: Second Edition

Umfang: XI, 427 Seiten; Illustrationen; 4178 x 254 mm 1015 g

Sprache: Englisch

ISBN: 9781493971701; 1493971700

Verlags-, Produktions- oder Bestellnummern: Sonstige Nummer: Bestellnummer: 978-1-4939-7170-1
Sonstige Nummer: Bestellnummer: 86399361

RVK-Notation: WC 4150 : Allgemeines, Praktika; "Methods of biochemical analysis"
VS 5360 : Allgemeines

Schlagwörter: Arzneimittelsicherheit

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0 : Methods in molecular biology

Drug safety evaluation - [Second Edition]

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