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Medientyp:
Buch
Titel:
Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity
Enthält:
Regulatory T cells: molecular and cellular basis for immunoregulation -- Overview of LAG-3- expressing, IL-10-producing regulatory T cells -- Regulatory Dendritic Cells -- Role of PD-1 in immunity and diseases -- CTLA-4, an essential immune-checkpoint for T cell activation -- Tim-3, Lag-3, and TIGIT -- SOCS1: regulator of T cells in autoimmunity and cancer -- Mining the complex family of protein tyrosine phosphatases for checkpoint regulators in immunity -- Immune regulation by ubiquitin tagging as checkpoint code -- MicroRNA in Immune Regulation