The molecules of life: physical and chemical principles

Medientyp: Buch

Titel: The molecules of life : physical and chemical principles

Enthält: Biological molecules -- Energy and entropy -- Free energy -- Molecular interactions -- Kinetics and catalysis.
From genes to RNA and proteins -- Nucleic acid structure -- Glycans and lipids -- Protein structure -- Evolutionary variation in proteins -- Energy and intermolecular forces -- Entropy -- Linking energy and entropy : the Boltzmann Distribution -- Free energy -- Chemical potential and the drive to equilibrium -- Voltages and free energy -- Molecular recognition : the thermodynamics of binding -- Specificity of macromolecular recognition --Allostery -- The rates of molecular processes -- Principles of enzyme catalysis -- Diffusion and transport -- Folding -- Fidelity in DNA and protein synthesis.

Beteiligte: Kuriyan, John [VerfasserIn]; Konforti, Boyana [VerfasserIn]; Wemmer, David [VerfasserIn]

Erschienen: New York, NY [u.a.]: GS, Garland Science, [2013]

Umfang: xxii, 1008 Seiten; zahlr. Ill., graph. Darst; 28 cm

Sprache: Englisch

ISBN: 9780815341888; 0815341881; 9780815341895; 081534189X

RVK-Notation: WD 4150 : Molekularbiologie (hier nur einführende Werke, Lehrbücher, Übersichten über das Gesamtgebiet, sonst bei entsprechenden Systemstellen, z.B. Zellbiologie WE, Molekulargenetik WG 1700 ff.)

Schlagwörter: Biochemie > Methode > Genomik > Molekularbiologie > Biomolekül

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Beschreibung: "Key to making future advances in the areas of biochemistry and molecular medicine is a new generation of molecular biologists and biochemists who are able to harness the tools and insights of physics and chemistry to exploit the emergence of genomic and systems-level information in biology.The basic ideas of energy, entropy, equilibrium thermodynamics, transport processes and reaction kinetics are closely related to exciting issues in contemporary biology, such as protein folding, chaperones and prion diseases, DNA polymerase and ribosome fidelity, DNA recognition, drug design, signal transduction, ion channel function, motor protein action and the versatility of enzyme mechanism. Providing this physical chemistry and biochemical foundation is The "Molecules of Life", a new undergraduate textbook for undergraduate students majoring in biology or pre-med. It deepens our understanding of how life functions by illuminating the physical principles underpinning biological phenomena"--Provided by publisher

"Key to making future advances in the areas of biochemistry and molecular medicine is a new generation of molecular biologists and biochemists who are able to harness the tools and insights of physics and chemistry to exploit the emergence of genomic and systems-level information in biology.The basic ideas of energy, entropy, equilibrium thermodynamics, transport processes and reaction kinetics are closely related to exciting issues in contemporary biology, such as protein folding, chaperones and prion diseases, DNA polymerase and ribosome fidelity, DNA recognition, drug design, signal transduction, ion channel function, motor protein action and the versatility of enzyme mechanism. Providing this physical chemistry and biochemical foundation is The "Molecules of Life", a new undergraduate textbook for undergraduate students majoring in biology or pre-med. It deepens our understanding of how life functions by illuminating the physical principles underpinning biological phenomena"--Provided by publisher

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